Low dose naltrexone appears to block the MU receptor in the brain which causes the decending pain.
Low dose naltrexone reduces chronic inflammation.
Low dose naltrexone has the potential to reverse nerve damage, whether from accidents, diabetes or other medical conditions.
Daily doses beyond 1.5mg should be dosed twice daily rather than all at one time.
Use of low-dose naltrexone in the management of chronic pain conditions: A systematic review – Elizabeth Hatfield DDS, Kristine Phillips DDS, Sahar Swidan PharmD, Lawrence Ashman DDS